{"id":1988,"date":"2022-09-06T14:27:37","date_gmt":"2022-09-06T14:27:37","guid":{"rendered":"https:\/\/neuropediatoolbox.org\/?p=1988"},"modified":"2024-11-20T19:17:07","modified_gmt":"2024-11-20T19:17:07","slug":"herencia-ligada-al-x-con-susceptibilidad-femenina","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/en\/herencia-ligada-al-x-con-susceptibilidad-femenina\/","title":{"rendered":"Herencia ligada al X con susceptibilidad femenina."},"content":{"rendered":"\n<p>En la herencia ligada al X, cl\u00e1sicamente se ha considerado que el patr\u00f3n de transmisi\u00f3n se produce de mujeres portadoras a varones afectos, y que por tanto, una mujer portadora tendr\u00eda una probabilidad de concebir un 50% de varones afectos y un 50% de mujeres portadoras. Sin embargo este supuesto s\u00f3lo se cumple en el caso de enfermedades recesivas. <\/p>\n\n\n\n<p>Adem\u00e1s, existen determinadas circustancias que pueden dar lugar a un patr\u00f3n de herencia \u00abinvertido\u00bb, con mujeres afectas y hombres no afectos. Este fen\u00f3meno parad\u00f3jico se produce en varias enfermedades neurol\u00f3gicas relevantes, la m\u00e1s conocida el s\u00edndrome de Rett. <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1497\/\">S\u00edndrome de Rett (MeCP2).<\/a><\/li>\n\n\n\n<li><a href=\"http:\/\/epilepsygenetics.net\/2018\/02\/08\/pcdh19-related-epilepsy-understanding-cellular-interference\/\">Epilepsia relacionada con la PCDH19.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK561282\/\">Trastorno del neurodesarrollo relacionado con DDX3X. <\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK602610\/\" title=\"\">Trastorno del neurodesarrollo relacionado con CDKL5.<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK1472\/\">Incontinentia pigmenti.<\/a><\/li>\n<\/ul>\n\n\n<div id=\"zotpress-b4b88a18e59dd16d492b18b2ed0b60df\" class=\"zp-Zotpress zp-Zotpress-Bib 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id=\"zp-ID-1988-332710-FCJHKFGF\" data-zp-author-date='Migeon-2020-07' data-zp-date-author='2020-07-Migeon' data-zp-date='2020-07' data-zp-year='2020' data-zp-itemtype='journalArticle' class=\"zp-Entry zpSearchResultsItem\">\n<div class=\"csl-bib-body\" style=\"line-height: 1.35; \">\n  <div class=\"csl-entry\" style=\"clear: left; \">\n    <div class=\"csl-left-margin\" style=\"float: left; padding-right: 0.5em; text-align: right; width: 1em;\">1.<\/div><div class=\"csl-right-inline\" style=\"margin: 0 .4em 0 1.5em;\">Migeon BR. X-linked diseases: susceptible females. Genetics in Medicine [Internet]. 2020 July [cited 2021 Apr 5];22(7):1156\u201374. Available from: <a class='zp-ItemURL' href='https:\/\/www.nature.com\/articles\/s41436-020-0779-4'>https:\/\/www.nature.com\/articles\/s41436-020-0779-4<\/a><\/div>\n  <\/div>\n<\/div>\n\t\t\t\t<\/div><!-- .zp-Entry .zpSearchResultsItem -->\n\t\t\t<\/div><!-- .zp-zp-SEO-Content -->\n\t\t<\/div><!-- .zp-List -->\n\t<\/div><!--.zp-Zotpress-->\n\n\n","protected":false},"excerpt":{"rendered":"<p>En la herencia ligada al X, cl\u00e1sicamente se ha considerado que el patr\u00f3n de transmisi\u00f3n se produce de mujeres portadoras a varones afectos, y que por tanto, una mujer portadora tendr\u00eda una probabilidad de concebir un 50% de varones afectos y un 50% de mujeres portadoras. Sin embargo este supuesto s\u00f3lo se cumple en el &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/neuropediatoolkit.org\/en\/herencia-ligada-al-x-con-susceptibilidad-femenina\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> \u00abHerencia ligada al X con susceptibilidad femenina.\u00bb<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":2267,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[44],"tags":[],"class_list":["post-1988","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-consejo-genetico-y-herencia","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/1988","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/comments?post=1988"}],"version-history":[{"count":1,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/1988\/revisions"}],"predecessor-version":[{"id":7708,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/1988\/revisions\/7708"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media\/2267"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media?parent=1988"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/categories?post=1988"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/tags?post=1988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}