{"id":3100,"date":"2022-10-15T15:08:11","date_gmt":"2022-10-15T15:08:11","guid":{"rendered":"https:\/\/neuropediatoolbox.org\/?p=3100"},"modified":"2026-06-22T20:07:27","modified_gmt":"2026-06-22T20:07:27","slug":"miastenia-congenita-y-trastorno-por-inactivacion-de-achr-fetal","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/en\/miastenia-congenita-y-trastorno-por-inactivacion-de-achr-fetal\/","title":{"rendered":"Dyke-Davidoff-Masson syndrome."},"content":{"rendered":"<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"532\" height=\"334\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-25.png\" alt=\"\" class=\"wp-image-3101\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-25.png 532w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-25-300x188.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-25-18x12.png 18w\" sizes=\"(max-width: 532px) 100vw, 532px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"528\" height=\"301\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-26.png\" alt=\"\" class=\"wp-image-3102\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-26.png 528w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-26-300x171.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/10\/imagen-26-18x10.png 18w\" sizes=\"(max-width: 528px) 100vw, 528px\" \/><\/figure>\n\n\n\n<p>Transient neonatal myasthenia is a rare complication of maternal myasthenia gravis. <\/p>\n\n\n\n<p>Around 10-15% of infants born to mothers with antibodies against acetylcholine receptor (AChR), and less frequently against muscle-specific kinase (MuSK). <\/p>\n\n\n\n<p>Symptoms are usually apparent from the 3rd day of life, and in almost all cases there is bilateral facial paresis and feeding difficulties. Symptoms usually resolve within the first month of life. <\/p>\n\n\n\n<p>However, in a small group of patients, a much more severe condition can occur, with fetal arthrogryposis and bulbofacial paresis persisting into adulthood, known as fetal AChR inactivation syndrome, caused by antibodies against the fetal gamma subunit, which is replaced in adults by the epsilon subunit. <\/p>\n\n\n\n<p>Receptor inactivation occurs due to exposure to specific antibodies during a critical period of development.<\/p>\n\n\n<div id=\"zotpress-45d63c2b24378bb08eb34360c1276cf9\" class=\"zp-Zotpress zp-Zotpress-Bib wp-block-group\">\n\n\t\t<span class=\"ZP_API_USER_ID ZP_ATTR\">19955111<\/span>\n\t\t<span class=\"ZP_ITEM_KEY ZP_ATTR\">{19955111:77IWNDPL}<\/span>\n\t\t<span class=\"ZP_COLLECTION_ID ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_TAG_ID ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_AUTHOR ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_YEAR ZP_ATTR\"><\/span>\n        <span class=\"ZP_ITEMTYPE ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_INCLUSIVE ZP_ATTR\">1<\/span>\n\t\t<span class=\"ZP_STYLE ZP_ATTR\">vancouver<\/span>\n\t\t<span class=\"ZP_LIMIT ZP_ATTR\">50<\/span>\n\t\t<span class=\"ZP_SORTBY ZP_ATTR\">default<\/span>\n\t\t<span class=\"ZP_ORDER ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_TITLE ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_SHOWIMAGE ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_SHOWTAGS ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_DOWNLOADABLE ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_NOTES ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_ABSTRACT ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_CITEABLE ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_TARGET ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_URLWRAP ZP_ATTR\"><\/span>\n\t\t<span class=\"ZP_FORCENUM ZP_ATTR\"><\/span>\n        <span class=\"ZP_HIGHLIGHT ZP_ATTR\"><\/span>\n        <span class=\"ZP_POSTID ZP_ATTR\">3100<\/span>\n\t\t<span class=\"ZOTPRESS_PLUGIN_URL ZP_ATTR\">https:\/\/neuropediatoolkit.org\/wp-content\/plugins\/zotpress\/<\/span>\n\n\t\t<div class=\"zp-List loading\">\n\t\t\t<div class=\"zp-SEO-Content\">\n\n\t\t\t<\/div><!-- .zp-zp-SEO-Content -->\n\t\t<\/div><!-- .zp-List -->\n\t<\/div><!--.zp-Zotpress-->","protected":false},"excerpt":{"rendered":"<p>Transient neonatal myasthenia is a rare complication of maternal myasthenia gravis. Around 10-15% of children born to mothers with anti-acetylcholine receptor (AChR) antibodies, and less frequently anti-muscle-specific kinase (MuSK). Symptoms are usually apparent from the 3rd day of life, and in almost all cases &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/neuropediatoolkit.org\/en\/miastenia-congenita-y-trastorno-por-inactivacion-de-achr-fetal\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> \"Congenital myasthenia and fetal AChR inactivation disorder.\"<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":3101,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[48,8,11],"tags":[],"class_list":["post-3100","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-especificamente-pediatricos","category-neonatal","category-neuromuscular","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/3100","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/comments?post=3100"}],"version-history":[{"count":3,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/3100\/revisions"}],"predecessor-version":[{"id":8452,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/3100\/revisions\/8452"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media\/3101"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media?parent=3100"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/categories?post=3100"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/tags?post=3100"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}