{"id":3512,"date":"2022-11-02T22:27:05","date_gmt":"2022-11-02T22:27:05","guid":{"rendered":"https:\/\/neuropediatoolbox.org\/?p=3512"},"modified":"2026-09-06T00:53:21","modified_gmt":"2026-09-06T00:53:21","slug":"pocs","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/en\/pocs\/","title":{"rendered":"CSWS"},"content":{"rendered":"<h2>POCS: Continuous Wave Point of Dream<\/h2>\n<p>Spike continuous sleep (POCS) is an age-dependent epileptic encephalopathy characterized by the presence of status epilepticus during deep sleep, with important cognitive-behavioral repercussions. It is also known as Penelope syndrome. Landau-Kleffner syndrome (or epilepsy-aphasia spectrum) is a subtype of this disease, in which the neurological deficit is a sensory aphasia.<\/p>\n<h2>Clinical Features<\/h2>\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"600\" height=\"277\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/imagen-28.png\" alt=\"\" class=\"wp-image-3514\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/imagen-28.png 600w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/imagen-28-300x139.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/imagen-28-18x8.png 18w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><figcaption>EEG tracing during sleep with ESES.<\/figcaption><\/figure>\n<p>The EEG tracing during sleep in POCS shows continuous wave activity, characterized by beta and gamma waves. This distinct pattern differs from the typical activity of deep sleep, which is dominated by delta waves.<\/p>\n<h2>Clinical Course<\/h2>\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"786\" height=\"575\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/Imagen-de-WhatsApp-2022-11-02-a-las-12.36.37.jpg\" alt=\"\" class=\"wp-image-3513\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/Imagen-de-WhatsApp-2022-11-02-a-las-12.36.37.jpg 786w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/Imagen-de-WhatsApp-2022-11-02-a-las-12.36.37-300x219.jpg 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/Imagen-de-WhatsApp-2022-11-02-a-las-12.36.37-768x562.jpg 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2022\/11\/Imagen-de-WhatsApp-2022-11-02-a-las-12.36.37-16x12.jpg 16w\" sizes=\"(max-width: 786px) 100vw, 786px\" \/><figcaption>Characteristic clinical course of the disease.<\/figcaption><\/figure>\n<p>The clinical course of POCS is generally progressive, with an initial stage of normal development followed by a decline in intellectual level and development. Sensory aphasia can manifest as difficulties understanding and responding to verbal languages.<\/p>\n<h2>Diagnosis and Treatment<\/h2>\n<p>The diagnosis of POCS is based on clinical evaluation, EEG tracing during sleep, and the evolution of the clinical course. Treatment may include anti-seizure medications such as valproate or lamotrigine, as well as cognitive-linguistic therapies to improve aphasic skills.<\/p>\n<h2>Patients Association<\/h2>\n<p>There are POCS patient associations that provide information and support to those affected. One of these is the Epileptic Encephalopathy with POCS Association (http:\/\/sindromepocs.org), which offers educational resources and a community to share experiences.<\/p>","protected":false},"excerpt":{"rendered":"<p>POCS: Continuous Wavy Sleep Spike Continuous wave sleep spike (POCS) is an age-dependent epileptic encephalopathy characterized by the presence of status epilepticus during deep sleep, with important cognitive-behavioral repercussions. It is also known as Penelope syndrome. Landau-Kleffner syndrome (or epilepsy-aphasia spectrum) is a subtype of this disease, in\u2026 <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/neuropediatoolkit.org\/en\/pocs\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> \u00abPOCS\u00bb<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":3515,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-3512","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-epilepsia","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/3512","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/comments?post=3512"}],"version-history":[{"count":2,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/3512\/revisions"}],"predecessor-version":[{"id":8658,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/3512\/revisions\/8658"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media\/3515"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media?parent=3512"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/categories?post=3512"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/tags?post=3512"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}