{"id":4713,"date":"2023-02-26T09:40:40","date_gmt":"2023-02-26T09:40:40","guid":{"rendered":"https:\/\/neuropediatoolbox.org\/?p=4713"},"modified":"2023-02-26T17:51:54","modified_gmt":"2023-02-26T17:51:54","slug":"trastornos-del-desarrollo-de-la-via-visual-y-el-quiasma-optico","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/en\/trastornos-del-desarrollo-de-la-via-visual-y-el-quiasma-optico\/","title":{"rendered":"Trastornos del desarrollo de la via visual (y el quiasma \u00f3ptico)."},"content":{"rendered":"\n

El albinismo oculocut\u00e1neo es un trastorno gen\u00e9tico que condiciona no s\u00f3lo una retinopat\u00eda, sino otras alteraciones en el desarrollo embriol\u00f3gico de la via visual, y por lo tanto del neurodesarrollo. La principal consecuencia es una p\u00e9rdida de la estereopsia.<\/p>\n\n\n\n

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1.<\/div>
Herrera E, Garcia-Frigola C. Genetics and development of the optic chiasm. FBL [Internet]. 2008 Jan 1 [cited 2023 Feb 26];13(5):1646\u201353. Available from: https:\/\/www.imrpress.com\/journal\/FBL\/13\/5\/10.2741\/2788<\/a><\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n<\/figcaption><\/figure>\n\n\n\n

Existen otros trastornos del neurodesarrollo que tambi\u00e9n comparten caracter\u00edsticas con el albinismo oculocut\u00e1neo, como el s\u00edndrome de Prader-Willi, en el que en ocasiones, se afecta el gen OCA2 por microdelecci\u00f3n, por lo que adem\u00e1s de presentar hipopigmentaci\u00f3n, tienen alteraciones del enrutamiento de los axones a trav\u00e9s del nervio \u00f3ptico. <\/p>\n\n\n\n

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Spritz RA, Bailin T, Nicholls RD, Lee ST, Park SK, Mascari MJ, et al. Hypopigmentation in the Prader-Willi Syndrome Correlates With P Gene Deletion But Not With Haplotype of the Hemizygous P Allele. Am J Med Genet [Internet]. 1997 July 11 [cited 2023 Feb 26];71(1):57\u201362. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6067925\/<\/a><\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n<\/figcaption><\/figure>\n\n\n\n

Este tipo de trastornos de la via visual pueden ponerse de manifiesto neurofisiol\u00f3gicamente, a trav\u00e9s de la realizaci\u00f3n de PEV con estimulaci\u00f3n diferencial de cada ojo por separado, y registro dicot\u00f3mico en ambos l\u00f3bulos occipitales. <\/p>\n\n\n\n

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Creel DJ, Bendel CM, Wiesner GL, Wirtschafter JD, Arthur DC, King RA. Abnormalities of the central visual pathways in Prader-Willi syndrome associated with hypopigmentation. N Engl J Med. 1986 June 19;314(25):1606\u20139.<\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

El albinismo oculocut\u00e1neo es un trastorno gen\u00e9tico que condiciona no s\u00f3lo una retinopat\u00eda, sino otras alteraciones en el desarrollo embriol\u00f3gico de la via visual, y por lo tanto del neurodesarrollo. La principal consecuencia es una p\u00e9rdida de la estereopsia. Existen otros trastornos del neurodesarrollo que tambi\u00e9n comparten caracter\u00edsticas con el albinismo oculocut\u00e1neo, como el s\u00edndrome … <\/p>\n

Continue reading \u00abTrastornos del desarrollo de la via visual (y el quiasma \u00f3ptico).\u00bb<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":4714,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[48,9,43],"tags":[],"class_list":["post-4713","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-especificamente-pediatricos","category-neurodesarrollo","category-trastornos-del-neurodesarrollo","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/4713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/comments?post=4713"}],"version-history":[{"count":0,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/posts\/4713\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media\/4714"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/media?parent=4713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/categories?post=4713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/en\/wp-json\/wp\/v2\/tags?post=4713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}