{"id":4713,"date":"2023-02-26T09:40:40","date_gmt":"2023-02-26T09:40:40","guid":{"rendered":"https:\/\/neuropediatoolbox.org\/?p=4713"},"modified":"2026-06-22T20:07:15","modified_gmt":"2026-06-22T20:07:15","slug":"trastornos-del-desarrollo-de-la-via-visual-y-el-quiasma-optico","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/fr\/trastornos-del-desarrollo-de-la-via-visual-y-el-quiasma-optico\/","title":{"rendered":"Troubles du d\u00e9veloppement de la voie visuelle (et du coquillage optique)."},"content":{"rendered":"\n

El albinismo oculocut\u00e1neo es un trastorno gen\u00e9tico que condiciona no s\u00f3lo una retinopat\u00eda, sino otras alteraciones en el desarrollo embriol\u00f3gico de la via visual, y por lo tanto del neurodesarrollo. La principal consecuencia es una p\u00e9rdida de la estereopsia.<\/p>\n\n\n\n

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Herrera E, Garcia-Frigola C. Genetics and development of the optic chiasm. FBL [Internet]. 2008 Jan 1 [cited 2023 Feb 26];13(5):1646\u201353. Available from: https:\/\/www.imrpress.com\/journal\/FBL\/13\/5\/10.2741\/2788<\/a><\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n<\/figcaption><\/figure>\n\n\n\n

Existen otros trastornos del neurodesarrollo que tambi\u00e9n comparten caracter\u00edsticas con el albinismo oculocut\u00e1neo, como el s\u00edndrome de Prader-Willi, en el que en ocasiones, se afecta el gen OCA2 por microdelecci\u00f3n, por lo que adem\u00e1s de presentar hipopigmentaci\u00f3n, tienen alteraciones del enrutamiento de los axones a trav\u00e9s del nervio \u00f3ptico. <\/p>\n\n\n\n

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Spritz RA, Bailin T, Nicholls RD, Lee ST, Park SK, Mascari MJ, et al. Hypopigmentation in the Prader-Willi Syndrome Correlates With P Gene Deletion But Not With Haplotype of the Hemizygous P Allele. Am J Med Genet [Internet]. 1997 July 11 [cited 2023 Feb 26];71(1):57\u201362. Available from: https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6067925\/<\/a><\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n<\/figcaption><\/figure>\n\n\n\n

Este tipo de trastornos de la via visual pueden ponerse de manifiesto neurofisiol\u00f3gicamente, a trav\u00e9s de la realizaci\u00f3n de PEV con estimulaci\u00f3n diferencial de cada ojo por separado, y registro dicot\u00f3mico en ambos l\u00f3bulos occipitales. <\/p>\n\n\n\n

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Creel DJ, Bendel CM, Wiesner GL, Wirtschafter JD, Arthur DC, King RA. Abnormalities of the central visual pathways in Prader-Willi syndrome associated with hypopigmentation. N Engl J Med [Internet]. 1986 June 19;314(25):1606\u20139. Available from: http:\/\/www.nejm.org\/doi\/abs\/10.1056\/NEJM198606193142503<\/a><\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"

L'\u00e2lbinisme ocular-cutan\u00e9 est un trouble g\u00e9n\u00e9tique qui conditionne non seulement une r\u00e9tinopathie, mais d'autres alt\u00e9rations dans le d\u00e9veloppement embryologique du parcours visuel et par cons\u00e9quent du neurod\u00e9veloppement. La principale cons\u00e9quence est une perte de la stereopsis. Il existe d'autres troubles du neurod\u00e9veloppement qui partagent \u00e9galement des caract\u00e9ristiques avec l'\u00e2lbinisme ocular-cutan\u00e9, comme le syndrome... <\/p>\n

Continuer la lecture \u00abTroubles du d\u00e9veloppement de la voie visuelle (et du chiasma optique).\u00bb<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":4714,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[48,9,43],"tags":[],"class_list":["post-4713","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-especificamente-pediatricos","category-neurodesarrollo","category-trastornos-del-neurodesarrollo","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts\/4713","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/comments?post=4713"}],"version-history":[{"count":3,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts\/4713\/revisions"}],"predecessor-version":[{"id":8429,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts\/4713\/revisions\/8429"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/media\/4714"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/media?parent=4713"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/categories?post=4713"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/tags?post=4713"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}