{"id":4953,"date":"2023-03-12T09:19:17","date_gmt":"2023-03-12T09:19:17","guid":{"rendered":"https:\/\/neuropediatoolbox.org\/?p=4953"},"modified":"2026-06-22T16:28:57","modified_gmt":"2026-06-22T16:28:57","slug":"inversiones-pericentricas","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/fr\/inversiones-pericentricas\/","title":{"rendered":"Inversions p\u00e9ricentrales et paracentrales."},"content":{"rendered":"<h2 class=\"wp-block-heading\">Inversions pericentrales \u00e0 parcencentra<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Les inversions chromosomiques sont des anomalies structurelles dans lesquelles un segment du chromosome est cass\u00e9 et r\u00e9ins\u00e9r\u00e9 dans une direction invers\u00e9e (180 degr\u00e9s)\u00a0:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n    <li><strong>InIn1<\/strong> Le segment invers\u00e9 <strong>comprend le centrom\u00e8re<\/strong>. Il existe un risque de donner naissance \u00e0 des gam\u00e8tes d\u00e9s\u00e9quilibr\u00e9s avec des duplications et des d\u00e9l\u00e9tions partielles apr\u00e8s croisement m\u00e9iotique, ce qui peut provoquer des avortements ou une prog\u00e9niture affectivement dysmorphique.<\/li>\n    <li><strong>Inversion paracentrique\u00a0:<\/strong> Le segment invers\u00e9 <strong>n'inclut pas le centrom\u00e8re<\/strong>. Il produit des gam\u00e8tes digocentriques et acentriques apr\u00e8s recombinaison, qui sont g\u00e9n\u00e9ralement non viables, r\u00e9duisant ainsi la possibilit\u00e9 de vivre une prog\u00e9niture d\u00e9s\u00e9quilibr\u00e9e mais augmentant l'infertilit\u00e9.<\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>Inversions p\u00e9ricentriques et paracentriques Les inversions chromosomiques sont des anomalies structurelles dans lesquelles un segment du chromosome est bris\u00e9 et r\u00e9ins\u00e9r\u00e9 dans une direction invers\u00e9e (180 degr\u00e9s) : Inversion p\u00e9ricentrique : Le segment invers\u00e9 comprend le centrom\u00e8re. Il existe un risque de donner naissance \u00e0 des gam\u00e8tes d\u00e9s\u00e9quilibr\u00e9s avec des duplications et des d\u00e9l\u00e9tions partielles apr\u00e8s croisement m\u00e9iotique, ce qui peut\u2026 <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/neuropediatoolkit.org\/fr\/inversiones-pericentricas\/\" class=\"more-link\">Continuer la lecture<span class=\"screen-reader-text\"> \u00abInversions p\u00e9ricentriques et paracentriques.\u00bb<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":4954,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[10],"tags":[],"class_list":["post-4953","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-neurogenetica","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts\/4953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/comments?post=4953"}],"version-history":[{"count":2,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts\/4953\/revisions"}],"predecessor-version":[{"id":8290,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/posts\/4953\/revisions\/8290"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/media\/4954"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/media?parent=4953"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/categories?post=4953"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/fr\/wp-json\/wp\/v2\/tags?post=4953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}