{"id":7204,"date":"2024-01-30T14:14:47","date_gmt":"2024-01-30T14:14:47","guid":{"rendered":"https:\/\/neuropediatoolkit.org\/?p=7204"},"modified":"2024-02-08T21:34:15","modified_gmt":"2024-02-08T21:34:15","slug":"indicacion-de-cosegregacion","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/ru\/indicacion-de-cosegregacion\/","title":{"rendered":"\u041f\u0440\u0438\u0437\u043d\u0430\u043a \u043a\u043e\u0441\u0435\u0433\u0440\u0435\u0433\u0430\u0446\u0438\u0438."},"content":{"rendered":"<p class=\"wp-block-paragraph\">\u041f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u0438\u0435 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u043a\u043e\u0441\u0435\u0433\u0440\u0435\u0433\u0430\u0446\u0438\u0438 \u0438\u043c\u0435\u0435\u0442 \u0434\u0432\u0430 \u043e\u0441\u043d\u043e\u0432\u043d\u044b\u0445 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0420\u0435\u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438\u0432\u043d\u044b\u0439 \u0441\u043e\u0432\u0435\u0442. \u041f\u0443\u0442\u0435\u043c \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0447\u043b\u0435\u043d\u043e\u0432 \u0441\u0435\u043c\u044c\u0438 \u043c\u043e\u0436\u043d\u043e \u043f\u043e\u043b\u0443\u0447\u0438\u0442\u044c \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044e \u043e \u043d\u0430\u043b\u0438\u0447\u0438\u0438 \u0432 \u0441\u0435\u043c\u044c\u0435 \u0431\u0435\u0441\u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043d\u044b\u0445 \u043d\u043e\u0441\u0438\u0442\u0435\u043b\u0435\u0439, \u0432 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0441\u0443\u0449\u0435\u0441\u0442\u0432\u0443\u0435\u0442 \u0432\u044b\u0441\u043e\u043a\u0438\u0439 \u0440\u0438\u0441\u043a \u043f\u0435\u0440\u0435\u0434\u0430\u0447\u0438 \u043d\u0430\u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439. \u041d\u0435\u043e\u0431\u0445\u043e\u0434\u0438\u043c\u043e \u043f\u0440\u043e\u0432\u0435\u0440\u0438\u0442\u044c, \u0435\u0441\u0442\u044c \u043b\u0438 \u0432 \u0441\u0435\u043c\u044c\u0435 \u0440\u0435\u043f\u0440\u043e\u0434\u0443\u043a\u0442\u0438\u0432\u043d\u043e\u0435 \u043d\u0430\u043c\u0435\u0440\u0435\u043d\u0438\u0435. <\/li>\n\n\n\n<li>\u0420\u0435\u0430\u043d\u0430\u043b\u0438\u0437 \u0438 \u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u044f VSI. \u0412 \u0442\u0435\u0445 \u0432\u0430\u0440\u0438\u0430\u043d\u0442\u0430\u0445 \u043d\u0435\u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u043d\u043e\u0433\u043e \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u044f, \u0432 \u043a\u043e\u0442\u043e\u0440\u044b\u0445 \u0432\u0430\u0436\u043d\u043e \u0437\u043d\u0430\u0442\u044c, \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043b\u0438 \u044d\u0442\u043e \u0432\u0430\u0440\u0438\u0430\u043d\u0442\u043e\u043c de novo \u0438\u043b\u0438 \u043d\u0435\u0442, \u0434\u043b\u044f \u043f\u043e\u043b\u0443\u0447\u0435\u043d\u0438\u044f \u044d\u0442\u043e\u0439 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u0438 \u043c\u043e\u0436\u043d\u043e \u043f\u0440\u043e\u0432\u0435\u0441\u0442\u0438 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0435 \u043a\u043e\u0441\u0435\u0433\u0440\u0435\u0433\u0430\u0446\u0438\u0438. <\/li>\n\n\n\n<li>\u0412\u043e\u0437\u043d\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u0438\u0435 de novo \u044f\u0432\u043b\u044f\u0435\u0442\u0441\u044f \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u0435\u043c ACMG, \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u0435\u043c\u044b\u043c \u0432 \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u044f\u0445 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0441\u0442\u0438. \u0415\u0441\u043b\u0438 \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u044b\u0439 \u0430\u043d\u0430\u043b\u0438\u0437 \u043f\u0440\u0438\u0432\u043e\u0434\u0438\u0442 \u043a \u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u043a\u0430\u0446\u0438\u0438 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0441\u0442\u0438, \u044d\u0442\u043e \u043c\u043e\u0436\u0435\u0442 \u0431\u044b\u0442\u044c \u0438\u043b\u0438 \u043d\u0435 \u0431\u044b\u0442\u044c \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u044b\u043c. \u042d\u0442\u043e \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u043e, \u0435\u0441\u043b\u0438 \u043f\u0440\u0438\u0432\u043e\u0434\u0438\u0442 \u043a \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044e \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f VSI \u043d\u0430 \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0435. <\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img fetchpriority=\"high\" decoding=\"async\" width=\"850\" height=\"442\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-19.png\" alt=\"\" class=\"wp-image-7269\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-19.png 850w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-19-300x156.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-19-768x399.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-19-18x9.png 18w\" sizes=\"(max-width: 850px) 100vw, 850px\" \/><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0412\u0435\u0440\u043e\u044f\u0442\u043d\u043e\u0441\u0442\u044c \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u043e\u0441\u0442\u0438 VSI \u043d\u0430\u0445\u043e\u0434\u0438\u0442\u0441\u044f \u0432 \u043e\u0447\u0435\u043d\u044c \u0432\u044b\u0441\u043e\u043a\u043e\u043c \u0434\u0438\u0430\u043f\u0430\u0437\u043e\u043d\u0435, \u043e\u0442 5 \u0434\u043e 95%, \u043f\u043e\u044d\u0442\u043e\u043c\u0443 \u043d\u0435 \u0432\u0441\u0435 VSI \u043e\u0434\u0438\u043d\u0430\u043a\u043e\u0432\u044b. \u041d\u0435\u043a\u043e\u0442\u043e\u0440\u044b\u0435 \u0438\u0437 \u043d\u0438\u0445 \u043e\u0447\u0435\u043d\u044c \u0431\u043b\u0438\u0437\u043a\u0438 \u043a \u0442\u043e\u043c\u0443, \u0447\u0442\u043e\u0431\u044b \u0441\u0447\u0438\u0442\u0430\u0442\u044c\u0441\u044f \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u0434\u043e\u0431\u0440\u043e\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u0435\u043d\u043d\u044b\u043c\u0438, \u0430 \u0434\u0440\u0443\u0433\u0438\u0435 \u0431\u043b\u0438\u0437\u043a\u0438 \u043a \u0442\u043e\u043c\u0443, \u0447\u0442\u043e\u0431\u044b \u0431\u044b\u0442\u044c \u043f\u0435\u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u043c\u0438 \u043a\u0430\u043a \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0435. \u041f\u043e\u044d\u0442\u043e\u043c\u0443 \u0432\u0430\u0436\u043d\u043e \u0437\u043d\u0430\u0442\u044c \u043f\u0440\u0438\u0447\u0438\u043d\u0443, \u043f\u043e \u043a\u043e\u0442\u043e\u0440\u043e\u0439 \u043e\u043d \u0431\u044b\u043b \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d \u043a\u0430\u043a VSI, \u0432 \u0447\u0430\u0441\u0442\u043d\u043e\u0441\u0442\u0438, \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u0438 ACMG, \u043a\u043e\u0442\u043e\u0440\u044b\u043c \u043e\u043d \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0443\u0435\u0442. <\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full\"><img decoding=\"async\" width=\"1024\" height=\"219\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-18.png\" alt=\"\" class=\"wp-image-7267\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-18.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-18-300x64.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-18-768x164.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-18-18x4.png 18w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u0422\u0430\u043a\u0436\u0435 \u0438\u043d\u0442\u0435\u0440\u0435\u0441\u043d\u043e \u043f\u0440\u043e\u0432\u0435\u0441\u0442\u0438 \u043f\u0440\u0435\u0434\u0432\u0430\u0440\u0438\u0442\u0435\u043b\u044c\u043d\u043e\u0435 \u043c\u043e\u0434\u0435\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435, \u0438\u0441\u043f\u043e\u043b\u044c\u0437\u0443\u044f \u043d\u0435\u043a\u043e\u0442\u043e\u0440\u0443\u044e \u043a\u043e\u043c\u043f\u044c\u044e\u0442\u0435\u0440\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u0443\u044e 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\u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0436\u0434\u0435\u043d\u0438\u0435 de novo, \u0442\u043e \u0435\u0441\u0442\u044c \u043f\u0443\u0442\u0435\u043c \u0441\u043e\u043e\u0442\u0432\u0435\u0442\u0441\u0442\u0432\u0438\u044f \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u044f\u043c PM6 \u0438\u043b\u0438 PS2.<\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-image size-full is-resized\"><img decoding=\"async\" width=\"900\" height=\"732\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-7.png\" alt=\"\" class=\"wp-image-7243\" style=\"width:800px;height:auto\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-7.png 900w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-7-300x244.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-7-768x625.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-7-15x12.png 15w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/><\/figure>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"244\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-8-edited.png\" alt=\"\" class=\"wp-image-7245\" style=\"width:510px;height:auto\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-8-edited.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-8-edited-15x12.png 15w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u041f\u0440\u0438\u043c\u0435\u0440: \u0432\u0430\u0440\u0438\u0430\u043d\u0442, \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u043a\u0430\u043a \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u043f\u043e\u0441\u043b\u0435 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u044f PS2 \u043f\u0435\u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439. <\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"465\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-1024x465.png\" alt=\"\" class=\"wp-image-7250\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-1024x465.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-300x136.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-768x349.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-1536x698.png 1536w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-18x8.png 18w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12-1568x713.png 1568w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-12.png 1837w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"453\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-1024x453.png\" alt=\"\" class=\"wp-image-7251\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-1024x453.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-300x133.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-768x340.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-1536x679.png 1536w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-18x8.png 18w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13-1568x693.png 1568w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-13.png 1807w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"458\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-1024x458.png\" alt=\"\" class=\"wp-image-7252\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-1024x458.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-300x134.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-768x343.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-1536x687.png 1536w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-18x8.png 18w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14-1568x701.png 1568w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-14.png 1800w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u041f\u0440\u0438\u043c\u0435\u0440 2: \u0412\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439 \u0432\u0430\u0440\u0438\u0430\u043d\u0442, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u043f\u0435\u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"464\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-1024x464.png\" alt=\"\" class=\"wp-image-7247\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-1024x464.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-300x136.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-768x348.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-1536x696.png 1536w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-18x8.png 18w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9-1568x711.png 1568w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-9.png 1875w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"475\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-1024x475.png\" alt=\"\" class=\"wp-image-7249\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-1024x475.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-300x139.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-768x356.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-1536x712.png 1536w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-18x8.png 18w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11-1568x727.png 1568w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-11.png 1879w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"472\" src=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-1024x472.png\" alt=\"\" class=\"wp-image-7248\" srcset=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-1024x472.png 1024w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-300x138.png 300w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-768x354.png 768w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-1536x708.png 1536w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-18x8.png 18w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10-1568x722.png 1568w, https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/image-10.png 1845w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<div data-wp-interactive=\"core\/file\" class=\"wp-block-file\"><object data-wp-bind--hidden=\"!state.hasPdfPreview\" hidden class=\"wp-block-file__embed\" data=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/Implementation-of-ACMG-Guidelines-1-1.pdf\" type=\"application\/pdf\" style=\"width:100%;height:600px\" aria-label=\"\u0412\u043d\u0435\u0434\u0440\u0435\u043d\u0438\u0435 \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0439 ACMG-1-1.\"><\/object><a id=\"wp-block-file--media-15288021-6285-460a-8cf6-c1ac6eac7bf5\" href=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/Implementation-of-ACMG-Guidelines-1-1.pdf\">\u0420\u0435\u0430\u043b\u0438\u0437\u0430\u0446\u0438\u044f-ACMG-Guidelines-1-1<\/a><a href=\"https:\/\/neuropediatoolkit.org\/wp-content\/uploads\/2024\/02\/Implementation-of-ACMG-Guidelines-1-1.pdf\" class=\"wp-block-file__button wp-element-button\" download aria-describedby=\"wp-block-file--media-15288021-6285-460a-8cf6-c1ac6eac7bf5\">\u0423\u0432\u043e\u043b\u044c\u043d\u044f\u0442\u044c<\/a><\/div>","protected":false},"excerpt":{"rendered":"<p>\u041f\u0440\u043e\u0432\u0435\u0434\u0435\u043d\u0438\u0435 \u043a\u043e\u0441\u0435\u0433\u0440\u0435\u0433\u0430\u0446\u0438\u043e\u043d\u043d\u044b\u0445 \u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u0439 \u0438\u043c\u0435\u0435\u0442 \u0434\u0432\u0430 \u043e\u0441\u043d\u043e\u0432\u043d\u044b\u0445 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f: \u041f\u0440\u0438\u043c\u0435\u0440: \u0432\u0430\u0440\u0438\u0430\u043d\u0442, \u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u043a\u0430\u043a \u0432\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u043f\u043e\u0441\u043b\u0435 \u043f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u044f \u043a\u0440\u0438\u0442\u0435\u0440\u0438\u044f PS2 \u043f\u0435\u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439. \u041f\u0440\u0438\u043c\u0435\u0440 2: \u0412\u0435\u0440\u043e\u044f\u0442\u043d\u043e \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439 \u0432\u0430\u0440\u0438\u0430\u043d\u0442, \u043a\u043e\u0442\u043e\u0440\u044b\u0439 \u043f\u0435\u0440\u0435\u043a\u043b\u0430\u0441\u0441\u0438\u0444\u0438\u0446\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u043a\u0430\u043a \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043d\u044b\u0439.<\/p>","protected":false},"author":1,"featured_media":7209,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[10],"tags":[],"class_list":["post-7204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-neurogenetica","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/posts\/7204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/comments?post=7204"}],"version-history":[{"count":8,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/posts\/7204\/revisions"}],"predecessor-version":[{"id":7274,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/posts\/7204\/revisions\/7274"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/media\/7209"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/media?parent=7204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/categories?post=7204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/ru\/wp-json\/wp\/v2\/tags?post=7204"}],"curies":[{"name":"WP","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}