{"id":8486,"date":"2026-07-17T05:52:35","date_gmt":"2026-07-17T05:52:35","guid":{"rendered":"https:\/\/neuropediatoolkit.org\/?p=8486"},"modified":"2026-09-24T15:35:25","modified_gmt":"2026-09-24T15:35:25","slug":"enfermedades-infecciosas-tropicales-durante-la-gestacion","status":"publish","type":"post","link":"https:\/\/neuropediatoolkit.org\/zh\/enfermedades-infecciosas-tropicales-durante-la-gestacion\/","title":{"rendered":"\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002"},"content":{"rendered":"

\u598a\u5a20\u671f\u759f\u75be\uff1a\u5bf9\u80ce\u513f\u795e\u7ecf\u53d1\u80b2\u7684\u5f71\u54cd\u548c\u9884\u9632\u7b56\u7565<\/h2>\n

\u611f\u67d3\u8005\u4e3a \u6076\u6027\u759f\u539f\u866b<\/em> \u598a\u5a20\u671f\u95f4\u662f\u6d41\u884c\u5730\u533a\u6700\u4e25\u91cd\u7684\u4ea7\u79d1\u5e76\u53d1\u75c7\u4e4b\u4e00\uff0c\u5176\u6df1\u8fdc\u5f71\u54cd\u8d85\u8d8a\u4e86\u56f4\u4ea7\u671f\uff0c\u5e76\u6df1\u523b\u5f71\u54cd\u513f\u7ae5\u7684\u795e\u7ecf\u53d1\u80b2\u3002\u5176\u5f71\u54cd\u4e0d\u4ec5\u9650\u4e8e\u5b55\u4ea7\u5987\u53d1\u75c5\u7387\u6216\u4f4e\u51fa\u751f\u4f53\u91cd\uff0c\u8fd8\u5ef6\u4f38\u5230\u6b63\u5728\u53d1\u80b2\u7684\u5927\u8111\u7ed3\u6784\uff0c\u4ea7\u751f\u8ba4\u77e5\u3001\u8fd0\u52a8\u548c\u8bed\u8a00\u7f3a\u9677\uff0c\u8fd9\u4e9b\u7f3a\u9677\u53ef\u80fd\u4f1a\u6301\u7eed\u5230\u5e7c\u513f\u671f\u53ca\u4ee5\u540e\u3002\u8fd9\u79cd\u60c5\u51b5\u5e76\u4e0d\u662f\u8d2b\u8840\u6216\u53d1\u70e7\u7684\u7b80\u5355\u526f\u4f5c\u7528\uff0c\u800c\u662f\u75c5\u539f\u4f53\u3001\u6bcd\u4f53\u514d\u75ab\u53cd\u5e94\u548c\u80ce\u513f\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u5728\u795e\u7ecf\u53d1\u751f\u548c\u7a81\u89e6\u53d1\u751f\u5173\u952e\u9636\u6bb5\u7684\u8106\u5f31\u6027\u4e4b\u95f4\u590d\u6742\u76f8\u4e92\u4f5c\u7528\u7684\u7ed3\u679c\u3002<\/p>\n

\u80ce\u76d8\u611f\u67d3\u7684\u75c5\u7406\u751f\u7406\u5b66\uff1a\u8d85\u8d8a\u8d2b\u8840<\/h3>\n

\u598a\u5a20\u671f\u759f\u75be\u5bf9\u80ce\u513f\u635f\u5bb3\u7684\u6838\u5fc3\u673a\u5236\u4e0d\u4ec5\u662f\u6bcd\u4f53\u8d2b\u8840\uff0c\u800c\u4e14 \u53d7\u611f\u67d3\u7684\u7ea2\u7ec6\u80de\u4e3b\u52a8\u9694\u79bb\u5728\u80ce\u76d8\u4e2d<\/strong>\u3002\u7684\u5bc4\u751f\u866b \u6076\u6027\u759f\u539f\u866b<\/em> \u8868\u8fbe\u7c98\u9644\u86cb\u767d\uff0c\u4f8b\u5982 VAR2CSA<\/em> \u4e0e\u5177\u4f53\u76f8\u5173\u7684 \u786b\u9178\u8f6f\u9aa8\u7d20 A (CSA)<\/em> \u5b58\u5728\u4e8e\u5408\u4f53\u6ecb\u517b\u5c42\u7684\u57fa\u5e95\u819c\u4e2d\uff0c\u5bfc\u81f4\u53d7\u611f\u67d3\u7684\u7ea2\u7ec6\u80de\u5728\u7ed2\u6bdb\u95f4\u9699\u4e2d\u5927\u91cf\u79ef\u805a\u3002\u8fd9\u79cd\u79ef\u805a\u4e0d\u4ec5\u963b\u788d\u80ce\u76d8\u8840\u6d41\uff0c\u800c\u4e14\u4f1a\u4ea7\u751f \u6709\u6bd2\u708e\u75c7\u5fae\u73af\u5883<\/strong> \u6539\u53d8\u8840\u80ce\u76d8\u5c4f\u969c\u3002\u6700\u8fd1\u5bf9\u4e4c\u5e72\u8fbe\u548c\u9a6c\u62c9\u7ef4\u4eba\u7fa4\u7684\u7814\u7a76\u8868\u660e\uff0c\u5728\u6d3b\u52a8\u6027\u611f\u67d3\u7684\u60c5\u51b5\u4e0b\uff0c\u8fd9\u79cd\u5fae\u8840\u7ba1\u963b\u585e\u4e0e\u5b50\u5bab\u80ce\u76d8\u8840\u6d41\u91cf\u51cf\u5c11\u9ad8\u8fbe 40% \u76f8\u5173\uff0c\u8fd9\u4f1a\u663e\u7740\u51cf\u5c11\u6c27\u6c14\u548c\u53f6\u9178\u3001\u94c1\u548c omega-3 \u8102\u80aa\u9178\u7b49\u5fc5\u9700\u8425\u517b\u7d20\u7684\u8f93\u9001\uff0c\u800c\u8fd9\u4e9b\u5bf9\u4e8e\u76ae\u8d28\u751f\u957f\u548c\u65e9\u671f\u9ad3\u9798\u5f62\u6210\u81f3\u5173\u91cd\u8981\u3002<\/p>\n

\u6b64\u5916\uff0c\u4e3b\u52a8\u611f\u67d3\u5f15\u53d1\u7684\u6bcd\u4f53\u514d\u75ab\u53cd\u5e94\u4f1a\u4ea7\u751f \u5168\u8eab\u708e\u75c7\u53cd\u5e94<\/strong> \u4fc3\u708e\u7ec6\u80de\u56e0\u5b50\u5982 TNF-\u03b1\u3001IL-1\u03b2 \u548c IFN-\u03b3 \u5347\u9ad8\u3002\u8fd9\u4e9b\u5206\u5b50\u53ef\u4ee5\u7a7f\u8fc7\u80ce\u76d8\u5c4f\u969c\u5e76\u76f4\u63a5\u4f5c\u7528\u4e8e\u80ce\u513f\u795e\u7ecf\u7cfb\u7edf\u3002\u5728\u5b9e\u9a8c\u6a21\u578b\u4e2d\uff0c\u4ea7\u524d\u66b4\u9732\u4e8e TNF-\u03b1 \u4e0e\u524d\u989d\u76ae\u8d28\u795e\u7ecf\u5143\u6570\u91cf\u51cf\u5c11\u548c\u795e\u7ecf\u5143\u8fc1\u79fb\u6539\u53d8\u6709\u5173\uff0c\u8fd9\u8868\u660e\u795e\u7ecf\u6bd2\u6027\u7684\u76f4\u63a5\u673a\u5236\u3002\u5728\u8d1d\u5b81\u548c\u52a0\u7eb3\u5bf9\u4eba\u7c7b\u8fdb\u884c\u7684\u7eb5\u5411\u7814\u7a76\u53d1\u73b0\uff0c\u5728\u598a\u5a20\u665a\u671f\u63a5\u89e6\u759f\u75be\u7684\u513f\u7ae5\u65b0\u751f\u513f\u8840\u6e05\u4e2d\u708e\u75c7\u6807\u8bb0\u7269\u7684\u6c34\u5e73\u8f83\u9ad8\uff0c\u8fd9\u4e0e 12 \u4e2a\u6708\u548c 24 \u4e2a\u6708\u65f6\u8ba4\u77e5\u53d1\u80b2\u6d4b\u8bd5\u7684\u8f83\u5dee\u5206\u6570\u663e\u7740\u76f8\u5173\u3002<\/p>\n

\u795e\u7ecf\u5fc3\u7406\u5b66\u5f71\u54cd\uff1a\u4e34\u5e8a\u8bc1\u636e\u548c\u8bc4\u4f30\u91cf\u8868<\/h3>\n

\u4ea7\u524d\u759f\u75be\u66b4\u9732\u5bf9\u795e\u7ecf\u7cfb\u7edf\u7684\u5f71\u54cd\u5e76\u4e0d\u5747\u5300\uff0c\u4e3b\u8981\u53d6\u51b3\u4e8e \u63a5\u89e6\u65f6\u95f4<\/strong>\u3002\u6570\u636e\u6765\u81ea Nema \u7b49\u4eba\u7684\u7cfb\u7edf\u8bc4\u4ef7\u3002 (2025) \u8868\u660e\uff0c\u598a\u5a20\u4e2d\u671f\u548c\u665a\u671f\u611f\u67d3\u7684\u5f71\u54cd\u6bd4\u598a\u5a20\u65e9\u671f\u611f\u67d3\u7684\u5f71\u54cd\u66f4\u4e25\u91cd\u3002\u8fd9\u662f\u56e0\u4e3a\u598a\u5a20\u4e2d\u671f\u662f\u76ae\u8d28\u901a\u8def\u5f62\u6210\u548c\u795e\u7ecf\u5143\u7f51\u7edc\u7ec4\u7ec7\u7684\u5173\u952e\u7a97\u53e3\uff0c\u800c\u598a\u5a20\u665a\u671f\u6070\u9022\u5927\u8111\u52a0\u901f\u751f\u957f\u548c\u9ad3\u9798\u5f62\u6210\u7684\u9636\u6bb5\u3002\u5728\u8fd9\u79cd\u60c5\u51b5\u4e0b\uff0c\u9a6c\u62c9\u7ef4\u7684\u7814\u7a76\u8868\u660e\uff0c\u6839\u636e\u4e0e \u8d1d\u5229\u5a74\u513f\u53d1\u80b2\u91cf\u8868\uff0c\u7b2c\u4e09\u7248 (BSID-III)<\/em>\u3002\u7279\u522b\u662f\u5728\u8bcd\u6c47\u4e60\u5f97\u548c\u590d\u6742\u6307\u4ee4\u7684\u7406\u89e3\u65b9\u9762\u5b58\u5728\u7f3a\u9677\uff0c\u8fd9\u8868\u660e\u5bf9\u4e0a\u989e\u533a\u548c\u97e6\u5c3c\u514b\u8bed\u8a00\u7cfb\u7edf\u6709\u5f71\u54cd\u3002<\/p>\n

\u5173\u4e8e\u8fd0\u52a8\u53d1\u80b2\uff0c\u7814\u7a76\u7ed3\u679c\u53d8\u5316\u8f83\u5927\u3002\u52a0\u7eb3\u7684\u4e00\u4e9b\u7814\u7a76\u62a5\u544a\u79f0\uff0c\u66b4\u9732\u513f\u7ae5\u7684\u72ec\u7acb\u884c\u8d70\u80fd\u529b\u5ef6\u8fdf\uff0c\u5e73\u5747\u5ef6\u8fdf 1.8 \u4e2a\u6708\uff0c\u800c\u5176\u4ed6\u7814\u7a76\u5219\u53d1\u73b0\u6ca1\u6709\u663e\u7740\u5dee\u5f02\u3002\u8fd9\u79cd\u5dee\u5f02\u53ef\u80fd\u662f\u7531\u4e8e\u65b9\u6cd5\u56e0\u7d20\u9020\u6210\u7684\uff0c\u4f8b\u5982\u4f7f\u7528\u4e0d\u540c\u7684\u91cf\u8868\uff08\u4f8b\u5982 \u683c\u91cc\u83f2\u65af\u5fc3\u7406\u53d1\u5c55\u91cf\u8868<\/em> \u4e0e \u4e39\u4f5b\u4e8c\u53f7<\/em>\uff09\uff0c\u6216\u8c03\u8282\u6548\u679c\u7684\u793e\u4f1a\u7ecf\u6d4e\u548c\u8425\u517b\u56e0\u7d20\u7684\u5f71\u54cd\u3002\u7136\u800c\uff0c\u5728\u63a7\u5236\u8fd9\u4e9b\u56e0\u7d20\u7684\u7814\u7a76\u4e2d\uff0c\u5f71\u54cd\u4ecd\u7136\u5b58\u5728\uff0c\u7279\u522b\u662f\u5bf9\u4e8e\u53cd\u590d\u611f\u67d3\u6216\u4e34\u5e8a\u75c7\u72b6\u66f4\u4e25\u91cd\uff08\u53d1\u70ed\u3001\u4e25\u91cd\u8d2b\u8840\uff09\u7684\u513f\u7ae5\u3002<\/p>\n

\u6df7\u6742\u56e0\u7d20\u548c\u5408\u5e76\u75c7\uff1a\u827e\u6ecb\u75c5\u6bd2\u548c\u8d2b\u8840\u7684\u4f5c\u7528<\/h3>\n

\u4f7f\u795e\u7ecf\u5f71\u54cd\u8bc4\u4f30\u590d\u6742\u5316\u7684\u4e00\u4e2a\u5173\u952e\u65b9\u9762\u662f \u759f\u75be\u4e0e\u5176\u4ed6\u5b55\u4ea7\u5987\u75be\u75c5\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528<\/strong>\u3002\u5408\u5e76\u611f\u67d3\u827e\u6ecb\u75c5\u6bd2\u662f\u4e00\u4e2a\u663e\u7740\u7684\u589e\u5f3a\u98ce\u9669\u56e0\u7d20\u3002\u5728\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u7387\u8f83\u9ad8\u7684\u4eba\u7fa4\u4e2d\uff0c\u4f8b\u5982\u5728\u5357\u975e\u548c\u80af\u5c3c\u4e9a\u7684\u4e00\u4e9b\u5730\u533a\uff0c\u4ea7\u524d\u63a5\u89e6\u759f\u75be\u4e0e\u795e\u7ecf\u5fc3\u7406\u635f\u4f24\u7684\u534f\u540c\u6548\u5e94\u6709\u5173\u3002\u8fd9\u662f\u56e0\u4e3a\u827e\u6ecb\u75c5\u6bd2\u4f1a\u635f\u5bb3\u514d\u75ab\u529f\u80fd\uff0c\u964d\u4f4e\u80ce\u76d8\u8c03\u8282\u708e\u75c7\u7684\u80fd\u529b\uff0c\u5e76\u53ef\u80fd\u589e\u52a0\u8840\u80ce\u76d8\u5c4f\u969c\u7684\u901a\u900f\u6027\u3002\u4e4c\u5e72\u8fbe\u7684\u7814\u7a76\u8868\u660e\uff0c\u540c\u65f6\u63a5\u89e6\u759f\u75be\u548c\u827e\u6ecb\u75c5\u6bd2\u7684\u513f\u7ae5\u5728\u667a\u5546\u6d4b\u8bd5\u4e2d\u8ba4\u77e5\u80fd\u529b\u5e73\u5747\u5ef6\u8fdf 3.5 \u5206\u3002 (WISC-R) 3 \u5c81\u65f6\uff0c\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u4ec5\u63a5\u89e6\u759f\u75be\u7684\u513f\u7ae5\u4e3a 1.2 \u5206\u3002<\/p>\n

\u540c\u6837\uff0c\u4e25\u91cd\u7684\u4ea7\u5987\u8d2b\u8840\uff08Hb < 8 g\/dL\uff09\u4e0d\u4ec5\u4f1a\u51cf\u5c11\u6c27\u6c14\u8f93\u9001\uff0c\u800c\u4e14\u8fd8\u4e0e\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff08\u4f8b\u5982 BDNF\uff08\u8111\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff09\uff09\u7684\u4ea7\u751f\u51cf\u5c11\u6709\u5173\uff0c\u800c BDNF\uff08\u8111\u6e90\u6027\u795e\u7ecf\u8425\u517b\u56e0\u5b50\uff09\u5bf9\u4e8e\u795e\u7ecf\u5143\u5b58\u6d3b\u548c\u7a81\u89e6\u53ef\u5851\u6027\u81f3\u5173\u91cd\u8981\u3002\u4ece\u8fd9\u4e2a\u610f\u4e49\u4e0a\u8bf4\uff0c\u8d2b\u8840\u4e0d\u4ec5\u4ec5\u662f\u4e25\u91cd\u7a0b\u5ea6\u7684\u6807\u5fd7\uff0c\u800c\u662f\u4e00\u4e2a \u6d3b\u6027\u81f4\u75c5\u56e0\u5b50<\/strong> \u5728 MRI \u7814\u7a76\u4e2d\uff0c\u8fd9\u4f1a\u5bfc\u81f4\u66b4\u9732\u513f\u7ae5\u7684\u8111\u5bb9\u91cf\u51cf\u5c11\u3002<\/p>\n

\u9884\u9632\u548c\u4e34\u5e8a\u7b56\u7565\uff1a\u4ece\u836f\u7269\u6cbb\u7597\u5230\u795e\u7ecf\u76d1\u6d4b<\/h3>\n

\u9884\u9632\u662f\u51cf\u8f7b\u8fd9\u4e9b\u5f71\u54cd\u7684\u6700\u6709\u529b\u5de5\u5177\u3002\u8fd9 \u5728\u598a\u5a20\u4e2d\u671f\u548c\u665a\u671f\u4f7f\u7528\u78fa\u80fa\u591a\u8f9b-\u4e59\u80fa\u5627\u5576 (SP) \u8fdb\u884c\u9884\u9632<\/strong>\u7ecf\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u63a8\u8350\uff0c\u5df2\u88ab\u8bc1\u660e\u53ef\u5c06\u4f4e\u51fa\u751f\u4f53\u91cd\u98ce\u9669\u964d\u4f4e 30-40%\uff0c\u5c06\u65b0\u751f\u513f\u6b7b\u4ea1\u98ce\u9669\u964d\u4f4e 25%\u3002\u7136\u800c\uff0c\u5176\u5bf9\u795e\u7ecf\u53d1\u80b2\u7684\u76f4\u63a5\u5f71\u54cd\u5374\u9c9c\u6709\u8bb0\u5f55\u3002\u76f8\u53cd\uff0c\u4f7f\u7528 \u7ecf\u6740\u866b\u5242\u5904\u7406\u7684\u868a\u5e10 (ITN)<\/strong> \u663e\u793a\u51fa\u66f4\u4e00\u81f4\u7684\u6548\u679c\uff1a\u52a0\u7eb3\u7684\u4e00\u9879\u8bd5\u9a8c\u8868\u660e\uff0c\u5728\u6574\u4e2a\u6000\u5b55\u671f\u95f4\u4f7f\u7528\u9a71\u866b\u868a\u5e10\u7684\u6bcd\u4eb2\u6240\u751f\u7684\u5b69\u5b50\u5728 24 \u4e2a\u6708\u65f6\u7684\u8ba4\u77e5\u53d1\u5c55\u91cf\u8868\u5e73\u5747\u9ad8\u51fa 2.1 \u5206\uff0c\u5373\u4f7f\u5728\u8c03\u6574\u4e86\u793e\u4f1a\u7ecf\u6d4e\u56e0\u7d20\u4e4b\u540e\u4e5f\u662f\u5982\u6b64\u3002<\/p>\n

\u6b64\u5916\uff0c \u4f7f\u7528\u6c2f\u55b9\u6216\u963f\u6258\u4f10\u918c-\u6c2f\u80cd\u8fdb\u884c\u5316\u5b66\u9884\u9632<\/strong> \u5728\u9ad8\u4f20\u8f93\u533a\u57df\uff0c\u5b83\u663e\u793a\u51fa\u989d\u5916\u7684\u4f18\u52bf\u3002\u8d1d\u5b81\u7684\u4e00\u9879\u7814\u7a76\u53d1\u73b0\uff0c\u6bcd\u4eb2\u63a5\u53d7\u65e9\u671f\u9884\u9632\u6027\u6cbb\u7597\uff08\u4ece\u598a\u5a20\u65e9\u671f\u5f00\u59cb\uff09\u7684\u5b69\u5b50\u5728 18 \u4e2a\u6708\u65f6\u8bed\u8a00\u53d1\u80b2\u8fdf\u7f13\u7684\u98ce\u9669\u964d\u4f4e\u4e86 35%\u3002\u8fd9\u51f8\u663e\u4e86\u91cd\u8981\u6027 \u65e9\u671f\u548c\u6301\u7eed\u5e72\u9884<\/strong>\uff0c\u4e0d\u4ec5\u662f\u4e3a\u4e86\u9884\u9632\u611f\u67d3\uff0c\u66f4\u662f\u4e3a\u4e86\u5728\u5173\u952e\u9636\u6bb5\u4fdd\u62a4\u5927\u8111\u53d1\u80b2\u3002<\/p>\n

\u4ece\u4e34\u5e8a\u89d2\u5ea6\u6765\u8bf4\uff0c\u5efa\u8bae \u4e3b\u52a8\u795e\u7ecf\u76d1\u6d4b<\/strong> \u6000\u5b55\u671f\u95f4\u63a5\u89e6\u759f\u75be\u7684\u513f\u7ae5\u3002\u8fd9\u5305\u62ec\u5e94\u7528\u7ecf\u8fc7\u9a8c\u8bc1\u7684\u91cf\u8868\uff0c\u4f8b\u5982 \u8d1d\u5229-III<\/em> \u5728 6\u300112 \u548c 24 \u4e2a\u6708\u65f6\uff0c\u4f7f\u7528\u4ee5\u4e0b\u5de5\u5177\u8fdb\u884c\u8bed\u8a00\u8bc4\u4f30 \u9ea6\u514b\u963f\u745f-\u8d1d\u8328\u4ea4\u9645\u53d1\u5c55\u91cf\u8868 (CDI)<\/em>\u3002\u5982\u679c\u53d1\u73b0\u53ef\u7591\u7684\u7ed3\u679c\uff0c\u5e94\u8003\u8651\u7531\u513f\u79d1\u795e\u7ecf\u5fc3\u7406\u5b66\u5bb6\u8fdb\u884c\u8bc4\u4f30\uff0c\u5982\u6709\u5fc5\u8981\uff0c\u5e94\u8003\u8651\u8fdb\u884c\u804c\u4e1a\u6cbb\u7597\u3001\u8a00\u8bed\u6cbb\u7597\u548c\u6559\u80b2\u652f\u6301\u7684\u65e9\u671f\u5e72\u9884\u3002<\/p>\n

\u603b\u4e4b\uff0c\u598a\u5a20\u671f\u759f\u75be\u4e0d\u4ec5\u662f\u4e00\u79cd\u4f20\u67d3\u75c5\uff0c\u800c\u4e14\u662f\u4e00\u79cd \u56f4\u4ea7\u671f\u795e\u7ecf\u7cfb\u7edf\u4e00\u7ea7\u5371\u9669\u56e0\u7d20<\/strong>\u3002\u5176\u5f71\u54cd\u57fa\u4e8e\u76f4\u63a5\u5f71\u54cd\u5927\u8111\u53d1\u80b2\u7684\u590d\u6742\u75c5\u7406\u751f\u7406\u673a\u5236\u3002\u6709\u6548\u7684\u9884\u9632\u4e0d\u4ec5\u53ef\u4ee5\u62ef\u6551\u751f\u547d\uff0c\u8fd8\u53ef\u4ee5\u4fdd\u62a4\u4e00\u4ee3\u4eba\u7684\u8ba4\u77e5\u548c\u795e\u7ecf\u6f5c\u529b\u3002\u5b9e\u65bd\u5168\u9762\u7684\u5b55\u4ea7\u5987\u548c\u65b0\u751f\u513f\u5065\u5eb7\u6218\u7565\uff0c\u91cd\u70b9\u662f\u65e9\u671f\u9884\u9632\u548c\u795e\u7ecf\u5fc3\u7406\u5b66\u76d1\u6d4b\uff0c\u5bf9\u4e8e\u51cf\u8f7b\u6d41\u884c\u5730\u533a\u795e\u7ecf\u6b8b\u75be\u7684\u8d1f\u62c5\u81f3\u5173\u91cd\u8981\u3002<\/p>\n

\n\n\t\t19955111<\/span>\n\t\t{19955111:CNYADQ5M}<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n <\/span>\n\t\t1<\/span>\n\t\t\u6e29\u54e5\u534e<\/span>\n\t\t50<\/span>\n\t\t\u9ed8\u8ba4<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n\t\t<\/span>\n <\/span>\n 8486<\/span>\n\t\thttps:\/\/neuropediatoolkit.org\/wp-content\/plugins\/zotpress\/<\/span>\n\n\t\t
\n\t\t\t
\n\t\t\t\t<\/span>%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22CNYADQ5M%22%2C%22library%22%3A%7B%22id%22%3A19955111%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Nema%20et%20al.%22%2C%22parsedDate%22%3A%222025-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%20style%3D%26quot%3Bclear%3A%20left%3B%20%26quot%3B%26gt%3B%5Cn%20%20%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-left-margin%26quot%3B%20style%3D%26quot%3Bfloat%3A%20left%3B%20padding-right%3A%200.5em%3B%20text-align%3A%20right%3B%20width%3A%201em%3B%26quot%3B%26gt%3B1.%26lt%3B%5C%2Fdiv%26gt%3B%26lt%3Bdiv%20class%3D%26quot%3Bcsl-right-inline%26quot%3B%20style%3D%26quot%3Bmargin%3A%200%20.4em%200%201.5em%3B%26quot%3B%26gt%3BNema%20S%2C%20Singhal%20R%2C%20Bharti%20PK%2C%20Nitika%20N.%20Malaria%20in%20pregnancy%20and%20its%20potential%20impact%20on%20neurodevelopment%20in%20children%3A%20a%20systematic%20review.%20Pediatr%20Res.%202025%20Oct%3B98%284%29%3A1257%26%23x2013%3B65.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%20%20%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Malaria%20in%20pregnancy%20and%20its%20potential%20impact%20on%20neurodevelopment%20in%20children%3A%20a%20systematic%20review%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shrikant%22%2C%22lastName%22%3A%22Nema%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Richa%22%2C%22lastName%22%3A%22Singhal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Praveen%20Kumar%22%2C%22lastName%22%3A%22Bharti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nitika%22%2C%22lastName%22%3A%22Nitika%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Malaria%20during%20pregnancy%20can%20have%20adverse%20effects%20on%20fetal%20development%2C%20but%20its%20impact%20on%20neurodevelopment%20remains%20unclear.%20Although%20some%20studies%20have%20explored%20the%20consequences%20of%20prenatal%20malaria%2C%20gaps%20persist%20due%20to%20inconsistencies%20in%20exposure%20timing%2C%20assessment%20methods%2C%20and%20study%20designs.%5CnMETHODS%3A%20This%20systematic%20review%20highlighted%20the%20gaps%20in%20six%20studies%20selected%20from%20an%20initial%20pool%20of%202029%20articles%2C%20offering%20clearer%20insights%20into%20the%20neurodevelopmental%20outcomes%20of%20prenatal%20malaria%20exposure.%5CnRESULTS%3A%20Studies%20from%20Uganda%2C%20Benin%2C%20Ghana%2C%20and%20Malawi%20show%20that%20malaria%20during%20pregnancy%20adversely%20impacts%20cognitive%2C%20motor%2C%20and%20behavioral%20development.%20Cognitive%20deficits%20were%20observed%20at%2012%20and%2024%20months%2C%20with%20some%20studies%20indicating%20long-term%20effects%20at%2036%20months.%20Motor%20development%20and%20language%20outcomes%20were%20variable%2C%20with%20language%20impairments%20linked%20to%20malaria%20acquired%20late%20in%20pregnancy.%5CnCONCLUSIONS%3A%20The%20review%20identifies%20gaps%20in%20research%2C%20such%20as%20the%20role%20of%20asymptomatic%20infections%2C%20exposure%20timing%2C%20and%20malaria%26%23039%3Bs%20interaction%20with%20maternal%20comorbidities%20like%20HIV.%20Potential%20mechanisms%20for%20neurodevelopmental%20deficits%20include%20placental%20dysfunction%20and%20inflammation%20impacting%20fetal%20brain%20development.%20However%2C%20methodological%20limitations%2C%20such%20as%20varying%20assessment%20tools%20and%20sample%20sizes%2C%20prevent%20conclusive%20evidence.%20The%20review%20calls%20for%20more%20longitudinal%20studies%20to%20understand%20the%20long-term%20effects%20of%20prenatal%20malaria%20better%20and%20guide%20interventions%20to%20improve%20child%20development%20in%20malaria-endemic%20regions.%5CnIMPACT%3A%20Prenatal%20malaria%20exposure%20is%20linked%20to%20cognitive%20deficits%2C%20with%20potential%20long-term%20effects%20on%20motor%20and%20language%20development.%20Late%20pregnancy%20malaria%20may%20have%20a%20stronger%20impact%20on%20language%20development%2C%20highlighting%20the%20importance%20of%20exposure%20timing.%20Mechanisms%20such%20as%20placental%20dysfunction%20and%20inflammation%20may%20disrupt%20fetal%20brain%20development%20and%20contribute%20to%20neurodevelopmental%20deficits.%20Future%20studies%20should%20prioritize%20longitudinal%20research%20using%20advanced%20methodologies%20to%20better%20understand%20the%20long-term%20effects%20of%20prenatal%20malaria%20exposure%20on%20neurodevelopment.%22%2C%22date%22%3A%222025-10%22%2C%22section%22%3A%22%22%2C%22partNumber%22%3A%22%22%2C%22partTitle%22%3A%22%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41390-025-03967-5%22%2C%22citationKey%22%3A%22%22%2C%22url%22%3A%22%22%2C%22PMID%22%3A%2240033081%22%2C%22PMCID%22%3A%22%22%2C%22ISSN%22%3A%221530-0447%22%2C%22language%22%3A%22eng%22%2C%22collections%22%3A%5B%22HRX9XVKI%22%5D%2C%22dateModified%22%3A%222026-07-17T05%3A44%3A07Z%22%7D%7D%5D%7D<\/span>\n\n\t\t\t\t
\n
\n
\n
1.<\/div>
Nema S\u3001Singhal R\u3001Bharti PK\u3001Nitika N\u3002\u598a\u5a20\u671f\u759f\u75be\u53ca\u5176\u5bf9\u513f\u7ae5\u795e\u7ecf\u53d1\u80b2\u7684\u6f5c\u5728\u5f71\u54cd\uff1a\u7cfb\u7edf\u8bc4\u4ef7\u3002\u513f\u79d1\u7814\u7a76\u4e2d\u5fc3\u3002 2025 \u5e74 10 \u6708\uff1b98(4):1257\u201365\u3002<\/div>\n <\/div>\n<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t<\/div>\n\n\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>\n

\ud83d\udd17 \u67e5\u9605\u94fe\u63a5\u8d44\u6e90\uff1a\u6000\u5b55\u671f\u95f4\u7684\u70ed\u5e26\u4f20\u67d3\u75c5\u3002<\/a><\/p>","protected":false},"excerpt":{"rendered":"

\u598a\u5a20\u671f\u759f\u75be\uff1a\u5bf9\u80ce\u513f\u795e\u7ecf\u53d1\u80b2\u7684\u5f71\u54cd\u548c\u9884\u9632\u7b56\u7565 \u598a\u5a20\u671f\u6076\u6027\u759f\u539f\u866b\u611f\u67d3\u662f\u6d41\u884c\u5730\u533a\u6700\u91cd\u8981\u7684\u4ea7\u79d1\u5e76\u53d1\u75c7\u4e4b\u4e00\uff0c\u5176\u6df1\u8fdc\u5f71\u54cd\u8d85\u8d8a\u4e86\u56f4\u4ea7\u671f\uff0c\u6df1\u523b\u5f71\u54cd\u513f\u7ae5\u7684\u795e\u7ecf\u53d1\u80b2\u3002\u5f71\u54cd\u4e0d\u662f\u2026\u2026 <\/p>\n

\u7ee7\u7eed\u9605\u8bfb ?????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????<\/span><\/a><\/p>","protected":false},"author":1,"featured_media":8487,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"categories":[52,8],"tags":[],"class_list":["post-8486","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-enfermedades-neuropediatricas-clasicas","category-neonatal","entry"],"_links":{"self":[{"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/posts\/8486","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/comments?post=8486"}],"version-history":[{"count":2,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/posts\/8486\/revisions"}],"predecessor-version":[{"id":8726,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/posts\/8486\/revisions\/8726"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/media\/8487"}],"wp:attachment":[{"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/media?parent=8486"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/categories?post=8486"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/neuropediatoolkit.org\/zh\/wp-json\/wp\/v2\/tags?post=8486"}],"curies":[{"name":"\u53ef\u6e7f\u6027\u7c89\u5242","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}