El principal factor de riesgo identificable en la historia clínica es la presencia de un hermano mayor con TEA, de forma que 1 de cada 5 niños con hermanos mayores con TEA, tendrán un diagnóstico de TEA a los 3 años, siendo más frecuente entre varones.
También es un factor de riesgo la edad parental en el momento de la concepción.
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