CHILDREN'S OSTEOPOROSIS = presence of fragility fractures. The International Society of Clinical Densitometry (ISCD), in its latest consensus in 2019, considers two possible conditions for the diagnosis of childhood osteoporosis: – Presence of one or more vertebral fractures in the absence of local disease or high-energy trauma. – BMD or CMO Z-score less than -2 (adjusted...
Category archives: Drugs
Coenzyme Q10 (Decorenone).
https://www.frontiersin.org/articles/10.3389/fnins.2023.1188839/full https://metabolicas.sjdhospitalbarcelona.org/ecm/defectos-sintesis-coenzima-q10/info/como-diagnostica-deficiencia-coenzima-q10 https://www.aeped.es/comite-medicamentos/pediamecum/coenzima-q10-ubidecarenona Indicaciones de tratamiento en neurología pediátrica:
Antiepileptic drugs.
Compassionate use, medication, foreign and drug use out-of-specification (out-of-the technical data sheet).
The AEMS link explains the three concepts, as well as in which cases it is necessary to request authorization and through which channels it should be done. Common examples in child neurology: Ethosuximide syrup (not marketed in Spain), available from hospital pharmacy as an foreign medication. Cannabidiol in Rett syndrome (for patients on treatment …
Master formula
Orphan drugs
https://www.ema.europa.eu/en/human-regulatory/overview/orphan-designation-overview