Infantile cerebral palsy and MRI. When to request genetic studies.

1. Introduction and Relevance of Neuroimaging Brain Magnetic Resonance (MRI) constitutes the first-line complementary test after the anamnesis and detailed neurological examination in all children with suspected Childhood Cerebral Palsy (CPI). It is estimated that MRI reveals pathogenic abnormalities in more than 80% of cases, providing guidance on the...

Malformations of cortical development.

Malformations of Cortical Development (CDM) Malformations of cortical development represent a broad group of structural abnormalities of the brain caused by the interruption of the biological processes of cell proliferation, neuronal migration or cortical organization during embryogenesis. Classification by Affected Stage Proliferation/Differentiation Anomalies: Microcephaly, megalencephaly, focal cortical dysplasia type II. Migration Anomalies…